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These are the 6 best call center software options for Zendesk in 2025:
1. Harmonix AI
2. Aircall
3. Talkdesk
4. Genesys Cloud
5. RingCentral Contact Center
6. 3CX
Many companies still manage their customer service channels in isolation, which complicates daily operations and limits access to useful information.
Using tools like email, phone calls or WhatsApp separately leads to a loss of time and efficiency.
In this context, having a Zendesk call center software is useful, but not always enough.
The lack of integration between channels can lead to duplicated tasks, impersonal responses and, in general, a less smooth experience for both the team and the customer.
In addition, without a solution that unifies interactions, strategic decision-making becomes slower and less accurate.
Having all the data scattered makes it harder to understand customer behavior and act quickly.
Throughout this article, we’ll explain how you can improve your current system, increase your team’s productivity and provide more effective support by integrating all your channels in a single environment.
The 6 Best Zendesk Call Center Software in 2025
1. Harmonix AI + Zendesk
Harmonix is not simply an AI-powered CRM. It’s a communication intelligence platform that installs on top of any CRM, including Zendesk, without replacing it.
This allows full use of its features without complex migrations or additional training.
With Harmonix, companies move past single-channel management. Instead, they can integrate calls, WhatsApp, emails, LinkedIn and video calls into the same system, bringing complete context and advanced automation to every interaction.
Thanks to its AI technology, users become faster and more productive, since much of the manual work is automated.
This results in faster responses, fewer errors and a better customer experience.
7 Key Benefits of Harmonix AI with Zendesk:
- Installs on top of Zendesk without replacing it, with an "augmented reality" effect.
- Digitalizes all communication channels and centralizes them within the current system.
- True omnichannel experience: calls, WhatsApp, email, LinkedIn and more, all connected.
- Smart automation of tasks, follow-ups, updates and responses.
- Increased team productivity: up to 40% more operational efficiency per user.
- Real-time insights and recommendations thanks to AI analysis.
- Automatic reports and summaries after every call or interaction.
Harmonix transforms Zendesk into an intelligent control center, ideal for sales, support or customer service teams seeking to unify channels and work with actionable data.
2. Aircall + Zendesk
Aircall is one of the most well-known integrations with Zendesk. It’s a cloud phone system designed to be easy to use and quick to implement.
Its focus is centered on calls, though it allows some customization with tags, notes and automatic recording. Its main advantage is its ease of use and seamless integration with Zendesk so everything is logged automatically.
Ideal for teams that need a light and reliable call solution, without complex setups.
3. Talkdesk + Zendesk
Talkdesk offers an AI-based contact center platform, aimed at companies with more complex customer service needs. Its integration with Zendesk allows agents to see the customer’s history directly on-screen during the call.
It has advanced features like smart routing, sentiment analysis and workflow automation, making it a good choice for large teams managing high call volumes.
It stands out for its customization capabilities and for offering a more sophisticated omnichannel experience.
4. Five9 + Zendesk
Five9 is a cloud-based call center software focused on efficiency and scalability. It integrates with Zendesk to log calls and customer data in real time.
It offers auto-dialers, recordings, live monitoring and supervision tools, making it a complete solution for medium to large contact centers.
Its strength lies in its ability to improve sales agents' operational productivity through automation and control features.
It offers automatic call dialer features, recordings, live monitoring and supervision tools, making it a complete solution for medium to large contact centers.
5. RingCentral + Zendesk
RingCentral stands out as a unified communication solution, allowing calls, video calls, messaging and collaboration.
Its integration with Zendesk enables agents to access the interaction history while making or receiving calls. It has solid omnichannel capabilities and is well-suited for teams that require smooth internal communication in addition to customer support.
Ideal for organizations that want to keep all communication channels connected and manage them from one place.
6. CloudTalk + Zendesk
CloudTalk is an affordable and easy-to-configure alternative. It focuses on VoIP calls and allows automatic tracking, recording and tagging of calls, integrating all this information into Zendesk.
Its features include call statistics, automated workflows and an intuitive interface.
It’s a good choice for startups or small businesses looking to improve phone service without complications.
Why Are So Many Companies Looking for a Zendesk Call Center Software?
The way companies communicate with their customers has completely changed. Today, users expect immediate, personalized responses from any channel.
Many companies that used to rely only on email or phone are now adopting solutions like Zendesk call center software to provide more fluid, efficient and connected service.
The key lies in centralizing all conversations, optimizing team resources and making smarter decisions based on real data.
What Is a Zendesk Call Center Software?
It’s a solution that allows you to manage calls directly from Zendesk, integrating them with the rest of the customer’s history.
Thanks to these tools, support teams can make and receive calls without leaving Zendesk, automatically log interactions and see the full context of each user in real time.
Some integrations, like Harmonix AI, go even further, connecting channels such as WhatsApp, LinkedIn, email and video calls into a single platform with automation and artificial intelligence features.
7 Key Benefits of Zendesk Call Center Software
1. Faster, More Personalized Support
The team has instant access to the customer’s full history. This allows for quicker responses, more accurate solutions and stronger relationships from the very first call.
2. Improved Team Productivity
By automating tasks like call logging or sending emails, agents spend more time on what really matters: helping the customer.
The result is a more efficient, less overloaded team.
3. Real Omnichannel Experience: All Channels in One Place
A software like Harmonix allows integration of calls, emails, WhatsApp and other channels into a single view.
This omnichannel approach not only enhances the customer experience, but also gives the team full context for each conversation.
4. AI That Understands the Entire Customer Journey
The most advanced tools use artificial intelligence to analyze calls, messages and emails.
This helps anticipate customer needs, detect patterns and suggest more effective responses.
5. Advanced Analysis and Reporting
The integration with Zendesk offers key metrics such as response times, call volumes and customer satisfaction. These stats help make better decisions and adjust strategy in real time.
6. Seamless Integration with CRMs and Sales Tools
The software connects smoothly with solutions like Salesforce, HubSpot or Pipedrive.
In the case of Harmonix, its advantage is that it installs on top of any existing CRM, without replacing it or requiring changes to current operations.
7. Total Accessibility and Mobility
Many of these systems are 100% cloud-based, allowing agents to work from anywhere and respond to customers even from their phones.
This is crucial for hybrid or distributed teams.
What Are the 3 Common Challenges When Implementing a Tool Like Zendesk?
Adopting a tool like Zendesk brings many benefits, but it can also pose certain challenges if not planned properly.
1. Resistance to Change
It’s common for some team members to resist adopting new tools. The key is to show how the software makes their work easier and improves the customer experience.
When intuitive, user-focused solutions are introduced, this barrier is greatly reduced.
2. Integration with Existing Systems
Many companies already use multiple systems like CRMs, sales platforms or analytics tools. Integrating Zendesk into these environments can be complex if the chosen software is not ready for it.
In that sense, Harmonix stands out by installing on top of any CRM without replacing it, which avoids costly projects and allows for faster adoption.
3. Training and Adaptation
Implementing a new tool requires training the team and adapting processes. Without guidance, users may become frustrated or fail to make the most of the system.
Some software like Harmonix make this transition easier with a user-friendly interface, automation and guided assistants, which speeds up the learning curve and improves adoption.
5 Key Factors for Choosing the Right Software
1. Team Size and Call Volume
A small business with 3 agents is not the same as a company with 100. Make sure the software can handle your current and future call volume without affecting performance.
2. Integration Needs with Other Systems
Evaluate whether you need to connect the tool with your CRM, ERP or other internal platforms. Smooth integration is essential to gain a 360° view of the customer and avoid duplicated tasks.
3. AI and Automation Features
A good software doesn’t just manage calls, it also automates processes, records data and suggests actions. These kinds of features are key for teams aiming to be faster and more efficient.
4. Scalability and Long-Term Support
Choose a solution that can grow with you. Whether it's in number of users, languages or functionalities, your tool should be able to adapt without needing to be replaced soon.
5. Total Cost vs. Return on Investment
Beyond the initial price, consider the return in productivity, error reduction and time savings. Tools like Harmonix AI prove that a smart investment pays off quickly thanks to the efficiency it generates.
By evaluating these factors, you’ll be much closer to choosing a solution that truly drives your business forward and makes your team’s work easier.
Why Is Harmonix AI + Zendesk a Winning Combination?
The integration of Harmonix AI with Zendesk offers a powerful solution for any team looking to work in a more agile, smart and connected way.
Unlike other tools, Harmonix does not replace your CRM. It installs on top of it, enhancing its functionality without altering existing processes. This makes its adoption quick and practical.
It also centralizes multiple communication channels like calls, emails, WhatsApp and LinkedIn, allowing decisions to be made with more information and responses to be faster. The result: a more productive team and more satisfied customers.
Use Cases: Sales Teams, Tech Support, Post-Sales
Sales: you can track progress, automate emails and log calls without leaving Zendesk. This helps close more deals in less time.
Technical Support: each ticket includes the full history of calls and messages, making support faster and more contextualized.
Post-Sales: agents can manage claims, renewals or upsells with all the information on hand, without needing to search across multiple systems.
More Productivity, Fewer Manual Tasks
With Harmonix AI, users save hours of work every week thanks to the automation of logging, summaries and follow-ups. Everything happens naturally, with no extra effort.
This frees up time for higher-value tasks, improves work quality and allows teams to focus on what truly matters: the customer.
Time Saved + Better Service = More Conversions
By having everything in one place and automating repetitive tasks, teams not only work faster, but work better.
Response times drop, personalization increases, and customers notice. This translates into a higher conversion rate and a much more professional experience.
Frequently Asked Questions (FAQs)
How does Harmonix improve sales analysis within Zendesk?
Harmonix analyzes all customer interactions and turns that information into useful insights to forecast sales, detect opportunities and improve processes, helping you enhance your sales analysis.
All of this without leaving the CRM.
Can I use Harmonix for customer prospecting from Zendesk?
Yes, Harmonix helps you with customer prospecting.
You can create contacts directly from calls, emails or WhatsApp, view automatic summaries and launch custom follow-ups with one click.
For more strategies on how to enhance outreach and lead generation, take a look at these 10 tips to improve sales prospecting.
Does Harmonix comply with data protection and GDPR?
Yes. Harmonix is designed to comply with data protection and privacy regulations, including GDPR, ensuring the secure handling of information.
How easy is it to integrate WhatsApp or email with Zendesk?
With Harmonix, it’s as simple as turning it on. The channels become connected in an omnichannel way, with no technical complications and no need to switch platforms.
Is it possible to work from a mobile device with this type of software?
Yes. Harmonix allows you to access the CRM and report activities from your mobile device, even by voice. Ideal for on-the-go or hybrid teams.
What if I already have a CRM in place?
No problem. Harmonix installs on top of your current CRM, like Salesforce, Dynamics or Zendesk, without replacing it. This avoids migrations and speeds up team adoption.